Vascular Biology
Cardiovascular diseases (CVD) cause more deaths per year than the next six leading causes of death combined. There is also strong evidence for a role of oxidative stress, a key focus at Oxford Biomedical Research, in the development of CVD. Emerging risk factors for CVD include isoprostanes, C-reactive proteins, fibrinogen and plasminogen activator inhibitor 1 (PAI-1). Fibrinogen and PAI-1 are key components of the highly regulated coagulation process. Elevated PAI-1 transcription has been reported to be caused by oxidative stress activation of the AP-1 response element. Vascular endothelial cells also play a key role in cancer by limiting the access of circulating cells to sub-endothelial space and thereby reducing tumor metastasis.
We offer a wide range of antibodies, purified and recombinant proteins, and immunoassay kits for studies of proteins involved in cardiovascular biology – including those that play key roles in coagulation and its regulation, as well as other proteins that have been recognized as important in cardiovascular pathobiology.
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PRODUCT |
CATALOG # |
SIZE |
PRICE |
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Anti Human PAI-1 (non-inhibitory) |
PI60 |
1.0 mg |
$1,065.00 |
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Anti Human PAI-1 (inhibitory) |
PI61 |
1.0 mg |
$1,065.00 |
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Anti Human PAI-1 (inhibitory) |
PI62 |
1.0 mg |
$1,065.00 |
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Anti Human PAI-1 |
PI63 |
1.0 mg |
$1,065.00 |
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Anti Rat PAI-1 (non-inhibitory) |
PI64 |
1.0 mg |
$1,065.00 |
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Anti Rat PAI-1 (inhibitory) Monoclonal Antibody |
PI65 |
1.0 mg |
$1,065.00 |
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Human PAI-1 (Glycosylated - Stable Mutant) |
PL75 |
0.5 mg |
$995.00 |
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Human PAI-1 (Glycosylated - Active Form) |
PL76 |
0.5 mg |
$995.00 |
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Human PAI-1 (Glycosylated - Latent Form) |
PL77 |
0.5 mg |
$995.00 |
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Human PAI-1 N-Terminal, Alexa Fluor 488 Labeled (Stable Mutant) |
PL78 |
0.5 mg |
$995.00 |
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Human PAI-1 N-Terminal, Alexa Fluor 488 Labeled (Active Wild Type) |
PL79 |
0.5 mg |
$995.00 |
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Human PAI-1 N-Terminal, Alexa Fluor 488 Labeled (Latent Wild Type) |
PL80 |
0.5 mg |
$995.00 |
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Human PAI-1 (N-terminal Alexa Fluor 594 labeled stable mutant) |
UP50 |
0.5 mg |
$995.00 |
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Human PAI-1 (N-terminal Alexa Fluor 594 labeled, active fraction) |
UP51 |
0.5 mg |
$995.00 |
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Human PAI-1 (N-terminal Alexa Fluor 594 labeled, latent fraction) |
UP52 |
0.5 mg |
$995.00 |
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Human Vitronectin (monomeric) |
GP01 |
0.5 mg |
$910.00 |
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Mouse Factor X |
CF38 |
0.1 mg |
$755.00 |
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Rat Factor X |
CF42 |
0.1 mg |
$730.00 |
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Anti Murine tPA |
PA62 |
1.0 mg |
$730.00 |
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Anti Murine tPA |
PA63 |
1.0 mg |
$730.00 |
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Anti Murine uPA (capture) |
PA70 |
1.0 mg |
$730.00 |
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Anti Murine uPA |
PA71 |
1.0 mg |
$730.00 |
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Human PAI-1 (active wild type) |
PI01 |
0.5 mg |
$730.00 |
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Human PAI-1 (latent wild type) |
PI02 |
0.5 mg |
$730.00 |
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Human PAI-1 (substrate form) P14 Arg |
PI04 |
0.5 mg |
$730.00 |
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Human PAI-1 (stable mutant) |
PI05 |
0.5 mg |
$730.00 |
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Human PAI-1 (6-X His Tag) |
PI06 |
0.5 mg |
$730.00 |
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PAI-1 mutant - minimal vitronectin binding |
PI07 |
0.5 mg |
$730.00 |
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Human PAI-1 (NBD P9 mutant) |
PI09 |
0.5 mg |
$730.00 |
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PAI-1 mutant reports vitronectin binding |
PI10 |
0.5 mg |
$730.00 |
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