Vascular Biology

Cardiovascular diseases (CVD) cause more deaths per year than the next six leading causes of death combined. There is also strong evidence for a role of oxidative stress, a key focus at Oxford Biomedical Research, in the development of CVD. Emerging risk factors for CVD include isoprostanes, C-reactive proteins, fibrinogen and plasminogen activator inhibitor 1 (PAI-1). Fibrinogen and PAI-1 are key components of the highly regulated coagulation process. Elevated PAI-1 transcription has been reported to be caused by oxidative stress activation of the AP-1 response element. Vascular endothelial cells also play a key role in cancer by limiting the access of circulating cells to sub-endothelial space and thereby reducing tumor metastasis.

We offer a wide range of antibodies, purified and recombinant proteins, and immunoassay kits for studies of proteins involved in cardiovascular biology – including those that play key roles in coagulation and its regulation, as well as other proteins that have been recognized as important in cardiovascular pathobiology.

Displaying 301-330 of 492 products
PRODUCT CATALOG # SIZE PRICE
Mouse Urokinase (Low Molecular Weight) UP37 0.05 mg $545.00
Mouse vitronectin total antigen ELISA assay GP49 Kit $505.00
Murine PAI-1 (stable mutant) PI18 0.5 mg $730.00
Murine PAI-1 (wild type active) PI16 0.5 mg $730.00
Murine PAI-1 (wild type latent) PI17 0.5 mg $730.00
Murine Pancreatic Elastase SP25 0.1 mg $610.00
Murine Plasmin PL30 1.0 mg $490.00
Murine Plasminogen PL28 1.0 mg $415.00
Murine Vitronectin (multimeric) GP04 0.1 mg $285.00
Non-enzymatic Human tPA PA44 0.1 mg $350.00
Non-enzymatic Mouse tPA PA76 0.1 mg $345.00
Non-enzymatic, non-cleavable Human tPA PA46 0.1 mg $350.00
Non-enzymatic, non-cleavable Mouse tPA PA50 0.1 mg $350.00
PAI-1 (NBD P1\' mutant) reports cleavage PI08 0.5 mg $730.00
PAI-1 mutant - minimal vitronectin binding PI07 0.5 mg $730.00
PAI-1 mutant reports vitronectin binding PI10 0.5 mg $730.00
Plasma, Human- PAI-1 depleted PL50 10 ml $290.00
Plasmin substrate VA13 25 mg $260.00
Porcine Fibrinogen FB03 25 mg $275.00
Porcine PAI-1 (wild type) PI22 0.5 mg $730.00
Porcine Pancreatic Elastase SP23 10 mg $250.00
Porcine Pancreatic Elastase, Immobilized SP31 1.0 ml $365.00
Porcine Vitronectin (urea prepared) GP33 0.1 mg $265.00
Rabbit anti human antiplasmin IgG fraction, biotin labeled VA32 1.0 mg $485.00
Rabbit anti human antiplasmin IgG fraction, FITC labeled VA33 1.0 mg $485.00
Rabbit anti Human Factor X antiserum CF29 1.0 ml $350.00
Rabbit anti Human Factor X IgG fraction, biotin labeled CF31 1.0 mg $405.00
Rabbit anti Human Factor X IgG fraction, FITC labeled CF32 1.0 mg $405.00
Rabbit anti Human Factor X IgG fraction, HRP labeled CF33 0.2 mg $405.00
Rabbit anti Human fibrinogen antiserum CT44 1.0 ml $365.00
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