Vascular Biology

Cardiovascular diseases (CVD) cause more deaths per year than the next six leading causes of death combined. There is also strong evidence for a role of oxidative stress, a key focus at Oxford Biomedical Research, in the development of CVD. Emerging risk factors for CVD include isoprostanes, C-reactive proteins, fibrinogen and plasminogen activator inhibitor 1 (PAI-1). Fibrinogen and PAI-1 are key components of the highly regulated coagulation process. Elevated PAI-1 transcription has been reported to be caused by oxidative stress activation of the AP-1 response element. Vascular endothelial cells also play a key role in cancer by limiting the access of circulating cells to sub-endothelial space and thereby reducing tumor metastasis.

We offer a wide range of antibodies, purified and recombinant proteins, and immunoassay kits for studies of proteins involved in cardiovascular biology – including those that play key roles in coagulation and its regulation, as well as other proteins that have been recognized as important in cardiovascular pathobiology.

Displaying 211-240 of 492 products
PRODUCT CATALOG # SIZE PRICE
Human PAI-1 (substrate form - P12 Arginine P14 Arginine double mutant) UP46 0.5 mg $730.00
Human PAI-1 (substrate form) P12 Glu PI03 0.5 mg $730.00
Human PAI-1 (substrate form) P14 Arg PI04 0.5 mg $730.00
Human PAI-1 (tPA Specific Mutant) PL87 0.5 mg $730.00
Human PAI-1 (vitronectin null binding mutant) UP45 0.5 mg $700.00
Human PAI-1 Depleted Plasma (Na Citrate) PI50 10 ml $310.00
Human PAI-1 N-Term cys mutant (latent wild type) PI81 0.5 mg $730.00
Human PAI-1 N-Terminal Biotin labeled (active wild type) PI83 0.5 mg $730.00
Human PAI-1 N-Terminal Biotin Labeled (latent wild type) PI84 0.5 mg $730.00
Human PAI-1 N-Terminal Biotin Labeled (stable mutant) PI85 0.5 mg $730.00
Human PAI-1 N-Terminal cys mutant (active wild type) PI80 0.5 mg $730.00
Human PAI-1 N-Terminal cys mutant (stable mutant) PI82 0.5 mg $730.00
Human PAI-1 N-Terminal, Alexa Fluor 488 Labeled (Active Wild Type) PL79 0.5 mg $995.00
Human PAI-1 N-Terminal, Alexa Fluor 488 Labeled (Latent Wild Type) PL80 0.5 mg $995.00
Human PAI-1 N-Terminal, Alexa Fluor 488 Labeled (Stable Mutant) PL78 0.5 mg $995.00
Human PAI-1 tPA Complex UP44 0.1 mg $365.00
Human PAI-1 tPA complex antigen assay UP47 Kit $505.00
Human PAI-1 uPA Complex PI99 0.1 mg $365.00
Human PAI-1 uPA complex antigen assay UP48 Kit $505.00
Human PAI-1, N-Terminal Fluorescein Labeled (Active Wild Type) PL82 0.5 mg $730.00
Human PAI-1, N-Terminal Fluorescein Labeled (Latent Wild Type) PL83 0.5 mg $730.00
Human PAI-1, N-Terminal Fluorescein Labeled (Stable Mutant) PL81 0.5 mg $730.00
Human PAI-1, Stable Mutant - stable PL86 0.5 mg $730.00
Human PAI-1/tPA Double Depleted Plasma PL88 10 ml $630.00
Human Plasminogen Total Antigen ELISA Assay PI97 Kit $370.00
Human Prorenin ELISA Kit RN35 Kit $505.00
Human Prorenin ELISA Kit for Non Plasma Samples RN36 Kit $505.00
Human Prorenin, C-terminal 8x His tag RN34 0.1 mg $265.00
Human Prorenin, Native RN33 0.1 mg $265.00
Human Prothrombin CT35 9.0 mg $320.00
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